What to prioritize, LOL, Variant, or Act 6?

I'm trying to put together a plan of attack for the next stage of my account and am just looking for some insight how to best spend my efforts (and units).

I have a decent-sized roster of 4*, 5* and 6* champs. Over 50 with a PI greater than 5k and dozen or so over 7k.

My top champs are:
R5 Blade
R4 Voodoo, Korg, Magik, Iceman & Hela
6* Angela, Yondu, Jane, Blackbolt & Miles

I have 100% explored Act 5 and all challenges in the last year or so.
I tried a LOL run a month ago and made it as far as Unstoppable Colossus before quitting (had used around 10 revives by that point). Can easily one-shot Rulk without boosts or redoing masteries.
Only attempted the first Emma fight with Gambit a few times (all failed).
First attempt at 6.1.1 got as far as Nebula before I was KOd.

I'm also free to play, so I want to make sure I don't get stuck "this close" to finishing and run out of resources. Would also appreciate any comments or insight into each.

Comments

B_Dizzle_01

Act 6 would be your easiest 1 pass. Then maybe do LOL 1 run. Then variant.

AzKicker316

Act 6 completion first. Research the best paths for your roster. Grind arenas to stock units and chips.

I’m a f2p player as well. I haven’t touched variant or lol. I found a Reddit post that went through the easy paths of act 6 and I’m finally on 6.1.6. I used just under 1k units so far, all on bosses.

SDP

LOL easy path for 4 T2 alpha and awakening gem to strengthen your roster. Then initial clear of Variant for three 2-3 rank up gems and 3-4 rank up gem to build a strong 5* roster for Act 6. Finally, initial clear of Act 6.

Depending on where your roster sits at this point you can determine the next step. I decided to go for 100% Variant to get another awakening gem, as well as 4-5 rank up gem.

TheSquish671

If you want to do at least variant chapter 1, since you have blade, you can take the magik path, and use gambit for the rest. I found the emma path harder because vision gained power from synthesis before i could even get to a bar of power.

Dexman1349

Not sure if I can get past these last 2. That will have to wait another day...