For questing : void - omega red - sabretooth - killmonger - winter soldier.
You can reverse regen, you have immunities of everything (bleed - potion - coldsnap - incirate) , you have true strike for evaders/autoblockers , and heavy hitter / power drainer with winter soldier.
Guys what do you think will be a great team of 5 champions in game Mine is - Nick fury, Ant man, ghost, Hood and wasp
If you use NF and Wasp a lot this team makes sense. If you want to to power your ghost to the maximum 2 YJ give good damage and Heimdal + Angela will give ghost a perma fury which is a good combo with antman. Also cheat death is in there
I am really loving the trinity between Venom, venom the duck and symbiote supreme and for normal missions you can add ghost and wasp, or Hood and antman, otherwhiles one of my favourite synergies atm is Killmonger, Sabretooth and Wintersoldier, but KM has to be 5 star imo, so that Ws gets plus 500% attack at 100 Combo (this is insane!)
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3 great champs that become even better with that synergy, and two versatile champs
You can reverse regen, you have immunities of everything (bleed - potion - coldsnap - incirate) , you have true strike for evaders/autoblockers , and heavy hitter / power drainer with winter soldier.
And I completed variant 2 because of it. Very powerful heavies from domino