I think that it is necessary to have the full trinity--personally, I never use hood--as it grants Ghost an additionally 25% attack at the start of the fight and an extra 15% per buff she has which really adds up fast. Ant-Man is essentially for good Ghost play, at least for me.
Like if I'm making a questing team, it wouldn't be worth it to bring anyone in but Wasp, right? Or do either Ant-Man or Hood really have that much to add?