What are you using them for? Who else is in your roster? Where are you in game progression?
Medusa shreds robots and has solid bleed. She's still awesome, regardless what some will say that she's outdated as her niche still has it's place and her regular damage and bleed is pretty high and consistent.
Sentinel gas a ton of utility and dual immunities. He's also mvp for 2 variants and a villain so he's good for the latest as well. Magneto will eat him for breakfast and medusa and nebula serve him up for lunch and dinner. Bit he's a general tank and has heal block, incinerate and shock.
Her dps can be very high and doesn’t rely on a cramped play style like parry heavy (unless you are trying to chain L3 and get 30 bleeds). She tears through robots with ease and shreds people with the L2 bleed very quickly. Bonus points if you have Karnak or black bolt on the team.
Medusa is a really great champion, but overall I'd say sentinel is better. He carried me through Variants 2, 3, 4 and 6. He was even my MVP for immunities when it came to becoming cavalier, overall insane base damage once he's ramped up, great crit resistance if you make mistakes, double immunities, DOT and Armor break, and heal block. The heal from the 2x LE is good but kind of inefficient.
It depends on the next content you are aiming for. Variants? Sentinel is an absolute MVP. Want to push through act 5,6.1,defense, general questing? Medusa is better.
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Medusa shreds robots and has solid bleed. She's still awesome, regardless what some will say that she's outdated as her niche still has it's place and her regular damage and bleed is pretty high and consistent.
Sentinel gas a ton of utility and dual immunities. He's also mvp for 2 variants and a villain so he's good for the latest as well. Magneto will eat him for breakfast and medusa and nebula serve him up for lunch and dinner. Bit he's a general tank and has heal block, incinerate and shock.