I am gonna explain each Awakening Ability to you.Guillotine 2099 - She Really doesn't need Awakening for offensive purposes. The only benefit you would be getting from awakening her would be the 10% of her max health which could help tank you special attacks including SP3's. Really nice safety net but definitely not compulsory.Hulk buster - You will Have massive regen if you awaken him. Based on a 5/65 champ at Sig 20 you will regen about 7100 health and at Sig 200 you get up to 14000. Again really beneficial for sustainability but not completely required.Sentinel - The only benefit you'll gain from Awakening him is shortened ramp up. Even then you have to bait at least 3-4 sp1's to completely ramp him up. If left unawakened you have to tap on opponents block for a long time but you cans still manage to ramp him up. Again not required but definitely makes the fight easy.In all none of them really need the awakening but benefit a lot from it especially Hulk buster. In my opinion save that gem for either Ghost or Guardian since they really do get a huge value from Thier awakening.