Depends on what the rest of your roster looks like and where you are in content. I personally wouldn't invest into any of these as 5*, but that doesn't mean they wouldn't help you.
Destroyer for his range of immunities. But like the other person said, don’t waste too many resources on said champs unless it is like a Shang-Chi, Onslaught or Hercules.
I'm only at a point where I can get 5* I'm in act 4 I think. The rest of my team is storm X, massacre, Luke cage, MCU captain marvel and warlock. I dunno if that's good, I dunno what I'm doing. I tend to just power up the ones I like using and see what happens.
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