From the Thor Ragnorak movie (Spoiler Alert) it seemed kinda obvious that the Sorcerer Supreme could easily defeat Thor if he wanted to. He could put Thor in an endless falling portal as he did with Loki and just forget about Thor or even drop him into the Sun. This is strictly going off the abilities of the MCU heroes and not necessarily the comic books
edit: Why is this post in the Bugs and Known issues section?
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edit: Why is this post in the Bugs and Known issues section?