I fought all the way to the Wolverine in Beyond Hope, got 9(!!) armor breaks up on wolverine with Despair Level 3... But Wolverine still kept regenerating.... With 9 debuffs he should not be regenerating anything (9 * 15% Regen Reduction), but he still was...
Unfortunately I spent quite a bit to even get to that point in revives, unlocking despair level 3, switching my masteries

Ghost Rider, King Groot, Punisher, Wolverine X-23, Hulk is my team, and it seems none of them can get by Wolverine now


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I have a video of this if it helps and created a trouble ticket. Thanks.