https://mobile.twitter.com/marvelchampions/status/1299812141072080897/video/1After thinking about the node combos on here, I have come to the conclusion that I think Torch will be the best option.

He could get 12% more damage on novas every time the 50% chance for incinerate triggers. Or if you use incinerates by themselves(no prefight), plus despair, you could lower her regen rate by 120% for the 6 incinerates that are usually on the opponent, plus 60 with maxed despair. So she will begin killing herself at .8% health per second.
Of course nick could work too.