Major bugs in Act 5, Chapter 2, map 3 and above
First off: I'm a 4 yr vet of this game, started a second account a few months ago and just recently started Act 5 on the second account. (Completed Act 5 a long time ago on my main account).
Issue: It seems that characters that have been "enhanced" in recent updates (ie. Venom) do not work properly in Act 5 content. Example that is super easy to reproduce: 5.2.3 -- try spidey with venom - he's the first fight out of the gate. Spidey should not be able to evade, but he does... a LOT. There were a ton of other issues that I noticed as I completed that path, but I won't be going any further until it gets fixed.
There is nothing in the node that should be reducing ability accuracy..etc.. so this is definitely a bug. I won't elaborate yet on all the other items, my guess is as soon as you figure out whats going on with spidey... you'll find everything else...