Personally aiming for a sabretooth - Killmonger - Omega red - Void - domino team. ST, omega and void benefit greatly in this team and KM, domino are pretty outstanding on their own. Think it covers almost every situation also! In terms of most helpful overall synergy heimdall, fury and cap IW have some great ones that can be shared with the rest of the party regardless of them being involved in it. Champ who benefits the most from specific synergies would probably be either ghost, ST or Thor rags. Never used either of darkhawk or nigh thrasher but apparently they are built in a similar mold
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It would be nice if you explain, at least a little, what you had in mind with these Champs instead of throwing only names at us.
Also Synergys ar related (most times (Aveangers!) ) to a specific Champ. So You meaning:
Heimdal - Whom Synergy?
Wasp - Ghost?
Ghost - Wasp?
Ghost - Hood?
Blade - GR?
Best Synergy package? (Spidy an Symbiotes came to my mind)
My opinion is it depens on Personal Skill and needs what is the "best" Synergy.
Hulk Cauze he got soooo many interactions.
Champ who benefits the most from specific synergies would probably be either ghost, ST or Thor rags. Never used either of darkhawk or nigh thrasher but apparently they are built in a similar mold