How high does 4* SL sig need to be to kill RoL Wolverine?
I'm pretty sure he only needs a couple of sigs in him to be effective, just need a high combo. But maybe try someone like Human Torch, duped Cap IW with a tech champ, or a Void? They can reverse the healing and beat Wolverine way quicker.
My 5/50 Starlord (about sig 60) did it in under 400 hits