Doom, CAIW or NF - who to rank?

This will be my first 5/65 so I'll be using whoever is best for Story quest, Act 5 (maybe 6), and of course AW as an attacker.

Comments

Oof, this is a tough one since there's no ghost or quake...

You didn't tell us if they are awakened or not

CAIW and NF needs their duped ability, Doom does not

NF if awakened, otherwise Doom. CapIW is amazing but you need him at high sig for better damage

Both my NF and CAIW are awoken. My CAIW is sig level 120.