This is going to be a controversial opinion as this game is so complex. My opinion is that this Professor X Synergy Team is the best questing team in the game. (Suicide specific)
Professor X
Colossus
Omega Red
AA
Red Magneto
Immunities - poison, bleed, incinerate, coldsnap, and 90% shock reduction
Utility- evade/miss counter, strongest AAR, Metal scrapper, thorns/passive damage counter.
Synergies
1. 100% special damage
2. Constant power gain
3. Constant regen from sides
4. 10% damage shield
5. OR + Colossus synergy
The regen is so strong from suicides that all champs are 100% health besides prof x at the end of each quest.
My evidence:
https://www.youtube.com/watch?v=OTcn-8w3AP0&feature=share