AQ and Catalyst Vault Connection Issues
Alliance Quest - Sometimes loading into fights will leave you stuck on the loading screen, loading indefinitely, forcing you to restart the game and lose half your champion's hp due to disconnecting. This doesn't happen frequently, only having happened to me once this past week, and once or twice in previous weeks, but it does happen.
Catalyst Vaults - The couple of times that I've played the Vaults, opening up selectors and picking a catalyst results in a bug opening the selector multiple times immediately afterwards and locking you into that screen, forcing you to exit the game and restart.