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Champ help for last two Epoch paths?

Trying to work on finishing Epoch, and I have two paths left: the 3 7* Cosmic Skill path, and the 2 7* Mutant Mystic path, both of which go through Cassie. For the Cosmic Skill, I see almost everyone recommend Bullseye or Serp, but I don't have a 7* version of either. Are they absolutely necessary for the run, or do they just cheese it?
And for the Mutant Mystic path, most everyone says that Juggs is a "must have", but it seems like the only thing he really helped with was Toad? I only have a 6R3 and a 7R1, so I'd really like to NOT use him if I can avoid it (I don't have any Mystic T6cc, so it'll be awhile before I can rank either version). Can he just be replaced with any viable champ?
And for the Mutant Mystic path, most everyone says that Juggs is a "must have", but it seems like the only thing he really helped with was Toad? I only have a 6R3 and a 7R1, so I'd really like to NOT use him if I can avoid it (I don't have any Mystic T6cc, so it'll be awhile before I can rank either version). Can he just be replaced with any viable champ?
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Serpent hard counters both Cassie and Prowler’s miss and evade, so he’s a cheese option for that path. Fights can be done with anyone it’s just much easier with him.
Juggs is really helpful for Heimdall. If you have a few unstoppables up, you can survive getting g clipper by his heavy if you make a mistake. Juggs also beats Ares like a rented mule.
Absent Juggs, I brought in Dragonman and Chee’ilth to SP1 spam Heimdall and it was the easiest fight on the path.
For the mutant, I used dazzler for that fight, i did the same thing, just hit till she dies. Dazzler also took the gwenpool and some other fights on that lane. I brought in dragon man as the mystic my team was dazz, onslaught and dragon man. Dragon man was used only for heimdall as I just spammed sp1 since it inflicts slow and just slowly chipped down heimdall. Onslaught took the fights dazzler could not take. Dazzler finished that gwenpool in 2 rotations, she was the best option in my opinion.