If you plan to give Angela 100+ sigs and rank up instantly then take her.
Otherwise take HB.
Since I already have all of the champs that I care for, first time awakening Angela is going to be great. If it's a dupe verse a new champ like Hulkbuster, that's a little bit trickier. I would proably do the new champ since Hulkbuster is a good champ.
new champ
HB is amazing
Generally the new champ is the right choice - and HB is a great champion, if nothing else he's consistently reliable for Tech EQ.
Duping Angela is a great move too, but she really needs a LOT of sigs (ideally 200) for her abilities to be fully reliable.