Chaos nodes and when they trigger
Chaos nodes, the ones that apply a random buff or debuff on both champs whenever a special is used, trigger the application right at the beginning, as soon as the special has been triggered. And in almost all cases, that's just fine. But it becomes a problem when the buff given is unstoppable. It's a problem because it totally prevents a special that would have absolutely landed from landing (unless they're especially stupid and just eat it anyways). But either way, whether they choose to block it or eat it, YOU the attacker are completely hosed unless you're lucky enough to be using a champ that isn't vulnerable after a special. This can result in an untimely loss of health or more likely on the tougher levels, a total KO.
I suggest a very very simple change that would make this much less annoying. Move the application of the buff/debuff from chaos to the end of the special. Easy-Peasey