YES! I took mine to rank 5 a few weeks ago and it's no question for me why he is in the conversation for best mutant champ in the game. The immunities and armor make him very sustainable, and when he gets ramped up he can really hit like a truck. Suicides are not necessary, but they of course will up his damage if you ever decide to go that route. When you say no synergies do you mean you don't have any of the synergy camps or you just don't plan on using them? Either way, he is a fantastic champ! If you have the resources, then I would recommend you go for it!