Apocalypse Disables the "Henchman" Node in V6
It would appear Apocalypse's -100% Purify Chance Ability is affecting the Henchman Node in Variant 6...
Henchman: When triggering a Fury Buff #Villain Attackers will Passively Purify all Debuffs.
There's a Path in 3.1 that has Henchman/Bio-Hazard/Rising Sun/Genius, he gains the Fury from Rising Sun on Every Hit but doesn't Purify any Poison Debuffs or Bleed Debuffs (while he's not activated Bleed Immune) nor any Debuffs from the Defender's Abilities... (Just to be clear it works fine on any other Attacker Champions)
Can't get Video of the Fight but it's so simple anyone could recreate the Issue, just bring Apocalypse into the Quest and fight the path that starts with Iron Fist and Spider-Man.
I know this probably won't get fixed because there's tons of other cases of Attacker Beneficial Node being shut down by Attacker Ability Accuracy Reduction and they haven't touched those, so this is more of a Warning for anyone planning to bring in Apocalypse expecting him to shrug off any Poison you may accidentally take...