Okay, so I get the basis of Professor X and his synergies seem legit, but how does the icon work when playing the other champs? For example:

There is a drug/synergy specific to Emma, but what do the numbers do? I notice that they decrease when I take damage, but why and what does that effect? I know I’m new to Prof X, but I feel like it doesn’t describe this in any of his champion info or synergy guide.
Thanks