Level 70 and Class Sub-Masteries
Increasing the level cap to 70 and each of those 10 levels gives you 1 Class mastery
A Class mastery is specific to its Class (obviously) and including the 6 in the game each class will have a total of 5 masteries with 5 levels each. They will cost Class Cores to unlock followed by a small to medium amount of units
Some ideas I've had are
Mutant:
OMEGA LEVEL: All Non Direct damage is increased by up to 20% (4% per level)
Cellular repair: A stronger varient of salve that responds to damage taken. Whenever mutants take damage they can repair up to 0.5% of their health per second up to a total of 10% of their health
Skill:
Weapon proficiency: critical rate and damage are boosted by 10% (2% per level) for all attacks involving a weapon (most special attacks for skill champions and even all attacks for MK and GP) (does not affect secondary damage like Bleed)
Tech:
Alternate Energy: All special attacks consume up to 10% less energy (2 per level)
Armor plating: all special attacks recieved deal up to 12.5% less damage
Cosmic:
Odin's Blessing: all buffs last up to 3 seconds longer (0.6 seconds a level)
Starlight: Enemy nullification has up to 25% chance to fail (5% per level)