I don't have a 5/65 Sentinel, or a 5/65 Ghost. I don't even have them as 5 stars. The only tech champ I used was Stark Spidey (who was AMAZING in this quest, lemme tell ya). There were no cash grab, unplayable nodes like in previous variant content.
Overall I didn't use a single unit on anything aside from a few energy refills.
The ONLY node that seemed unfair to me was the 1% regen, mighty charge, Rogue in 3.1 - That was the only fight that made me almost rage quit because it just seems almost impossible? After about 10 tries I got it down with a Rank 5 Starky with a 30% green boost and 15% attack boost - while running full suicides - SO a Rank 5 Starky with a 105% attack boost was just barely enough to get it down. I think that node needs to be looked at.
So yeah man, all the boss nodes were fun, I think the system of having the paths linked with the same purple nodes as opposed to each having their own orange node is just really nice. It felt like an uncollected quest where you need to bring a team to counter the node as opposed to having to bring something specific to each fight like in Variant 1.
What I LOVED about this quest, was that you got a little boost if you used tech champs, and Sentinel (when it worked), but if you didn't have the top tech champs, it literally didn't matter. I personally used Omega Red for 90% of all the fights, and then Starky for all the boss fights (Except Colossus, I used Darkhawk for him).

So great job Kabam on the best piece of Endgame content in recent memory.
Let's hope Act 6.3 looks similar.