Hard but definitely not impossible, Iceman makes him easy even as a 3 star it should be manageable, otherwise any strong 4/40s or 5/50s should take him down, whenever he gets his aura of incinerate just back up and play very defensively almost like you're trying to bait his special
What champs do you have at your dissposal? Iceman does have tripe immunity. Also depends on your skill. Just bait SP1s and SP2s and you're pretty much set. Regeneration is just like a reset, takes more time.
Heal block is the solution to his Regen. Unless you have gully in which case reverse healing is the solution. I only glanced but saw you have a 4* vision and a 4* cw. Both have heal block. As soon as he gets close to that threshold make sure you're in a position to intercept his next attack and for vision use his specials, for cw just launch a heavy attack.
Getting there will be the bigger issue if you just do that.
OG Vision or Ice Man would work. I used 3* and 4* GP for fun after finishing it with my r4 5* initially. You can do it! Understand how souls work with regeneration and make sure not to get hit or approach when aura of incineration is active.
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Getting there will be the bigger issue if you just do that.