Managing the Spite Node

I hate the Spite node—principally, because it punishes a core mechanic of any fight (in game or real life): evasion. When coupled with high attack opponents and/or organic power gainers, it can be a massive pain. Power Managers clearly are a huge asset, as well as champs who throw up few buffs of their own.
Other than removing Dex, who’s your go-to for Spite nodes and why? Who’s best by class? How do you tend to play it?
Dr. Zola
Other than removing Dex, who’s your go-to for Spite nodes and why? Who’s best by class? How do you tend to play it?
Dr. Zola
1
Comments
Tech: Spark
Science: CAIW
Mutant: Domino
Mystic: Magik
Cosmic: Another class
Skill: Blade, probably.
Mutant: Domino (parry Heavy, SP2 has taunt and she can make it fail)
Cosmic: Really terrible option against spite, not sure there is a good one here
Mystic: Dormamu, Magik
Science: Luke, Void, Cap IW Duped
Skill: Blade if they're villain or mystic, GP, KM SP2
Cosmic forget that all of them buffs themselves lol
Thank you all.
Dr. Zola
For AW on 44 ghost is great, and morningstar b/c you can kill them super quick