Hey there, you can find out more information about Mastery Cores here. Different cores are needed to unlock different Masteries. If you meet the prerequisites to unlock a Mastery and have enough cores to do so, you can click on the Mastery and hit the "Unlock" button to make that Mastery available to put points into. Then, if you have Mastery Points available, you can put points into the Mastery to activate it. Hope that helps clear things up!
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