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IS DUP 6* Guillotine WORTH R2?? NEED HELP

I'm THRILLED I dupd 6* Guilly & almost have resources to R2 her. other undup 6*s are Sentinel,RH,GG,Storm

other 5*s worth mentioning are R5 DrV
R4s Magik,SMse,Iceman,Quake
R3s dup GP,CM,WS,Venom,Hulk
undup Masacre,KM,imiw,Heimdall,medusa,GR,Hyp

Basically, 1/2 guys in new alli were QUICK shoot down R2ing Guilly,
citing low block, lack of armor break, nullify, & overall functionality.
(as compared to other Mystics) & in a game where U cant always see who your gonna fight, U would hit a brick wall,
if surprised with Omega Red,Cable,LC,Korg & many others

1/2 guys in my friends list said ABSOLUTELY DO IT, R2 her....
other 1/2, after they were done laughing, said NO, DONT R2 her.

Some argued 6*s are the future, some said its better to invest in 5* R5s.

HERE's my Questions

****Doesnt her 10% per 4 souls health steal WORK ON DAMAGE GIVEN?
As in, if I R2 & her HIT goes from 2,000 to 2,600
doesnt that mean, she' ll health steal slightly more health,
then she would at R1, because she's hitting harder at R2?****

8 souls = 20% health steal CHANCE? 12 souls = 30%? 16 souls = 40%?

in end game stuff, where you have to evade, ...about everything, with zero hits, & even block damage can take half your life during a fight,
wouldn't a dup R2 6* guilly be semi-god like ?

ANY whispers of a Guilly buff or game changing synergy on horizon ??
(aware of MS synergy, dont have as 5..fingers crossed)

with that champ list,... What would you do?
I noticed Venom has great synergies with both 6* GG & Guilly, .. R4 worthy?
(& Heindall also benefits guilly & ya cant beat whole team synergy)

Is there more value in R2ing Sentinel or RH? (assuming i ever pull a Domino)
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