Mastery Help

So i have been thinking about this alot lately ... I have done the initial clear of act 5 and will soon start the exploration ... And i might get into Arena Grinding in the coming months because I'll have a lot of free time ... So should i consider Suicides? I have Willpower and Recovery maxed ... Or should i consider only one of the suicides or none at all? ... The attack boost they give is huge but the DoT and recoil messes everything up ... I have a 5* Ghost and I've heard she can neglect the recoil damage too ... What should i do?
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