Ofcourse it depends on your roster. For me, I found regen champs to be the most useful for becoming uncollected, this is to save potions ofcourse. At the time I had a duped 5* OG Ironman and 4* X-23 doing most of the heavy lifting. now a days there's lots of great champs e.g Starky, Ghost, Corvus, Blade, etc..
Post your roster here and the community can best advise where to put your resources.
4* duped 5/50 Hyperion and OG Spiderman, 5* 3/45 Angela, 5* 2/35 unawakened Hawkeye and Nebula, 4* 4/40 duped Guillotine, 4* 4/40 unawakened X-23 , Sabretooth. These champs got me to 5.1.4, but by this point, I need some new tips.
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Post your roster here and the community can best advise where to put your resources.