Am I ready?

I got uncollected a while back and am now wondering if I’m ready to start 5.3. Based on the champs below do you think I could beat at least a couple quests of it? I heard it was much harder than 5.4.

Feel free to ask questions.

Feel free to ask questions.
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Comments
I focused on 5.4 (besides collector) and 5.2 before going on 5.3, helps when you're more developed.