In standar quests is always best looking for completion. The rewards and the benefits for the titles are much better. You should go for Act4 and when you stuck then try Act3 exploration, the same for Act 5, etc.
I am a newbie, being playing this game for 40-45 days , yet I completed act 4 as butter on bread, with 4*r4, shangchi, ibomb, venompool, sorcerer supreme and 5*r2 domino,(All unawakened) . didn't lose a single fight in whole act. Easy as it gets
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With that Roster You can take down Maestro
Edit: lol didn’t notice this was from 3 years ago. Hope you finished act 4.
my first post back from the dead