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Despair x Willpower: most useful?

I know both of them have their uses and it depends on which champs you use, but I need some help. It’s not easy to get 1.1k units to unlock both of them so I need to pick one for now. The champs that are part of my attack team are CAIW, Gwenpool, Warlock, Emma Frost and Sunspot. For now, I’m exploring act 4 and event quests. Any advices? Deep wounds and assassin are worthy too?
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CAIW inflicts a lot of debuffs when awakened, Sunspot inflicts a lot of incinerate debuffs, Gwenpool inflicts a lot of bleed debuffs.