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What is the best team to run against the De-Buffs in ACT-4.

Hi. I am facing an issue where I am able to do damage, but the De-Buffs on certain nodes - (Degeneration, Poison, Bleed, etc) disallow me to finish the job without going through 1.5 champions. The squad I am running now is-
Aegon (5* Duped) Rank 1/5 Level 25/25
Hyperion (4* Duped) Rank 4/5 Level 21/40
Black Widow CV (4*) Rank 4/5 Level 4/40
Captain America IW (4*) Rank 3/5 Level 40/40
Archangel (5*) Rank 1/5 Level 25/25
Even though I had a very god tier like team (according to some websites), I am still finding Act 4 tough. Hyperion can be interchanged with Medusa who is also 4* Duped 3/5 Level 30/30.
Any tips on Masteries to combat Debuffs or strategies?
Aegon (5* Duped) Rank 1/5 Level 25/25
Hyperion (4* Duped) Rank 4/5 Level 21/40
Black Widow CV (4*) Rank 4/5 Level 4/40
Captain America IW (4*) Rank 3/5 Level 40/40
Archangel (5*) Rank 1/5 Level 25/25
Even though I had a very god tier like team (according to some websites), I am still finding Act 4 tough. Hyperion can be interchanged with Medusa who is also 4* Duped 3/5 Level 30/30.
Any tips on Masteries to combat Debuffs or strategies?
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