Roster advice please


Which characters should my focus be on upgrading? I have beat act 4 and am working in exploration of it. Are my 3 5\*s good enough to be worth upgrading for long term gain? Or should I be more focused on the 4\*s? Or half and half? Advice please.
Also, any good guides for playing as KM or Luke Cage. Luke is just normal and use sp1 for the stun, right? What about KM?
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Claire is also definitely worth investing in. Will cover a lot of immunities, is sustainable, and arsenal of utility, and its utility you don’t really don’t really have covered
Nick Fury is you can get him awakened will crush everything
Here is the rest of my 4* roster. I also have an og cap, Sym Spidey, and Groot but I figured those weren't worth another picture.
Exploring Act 4 first is actually a good move as it will give you enough resources and an awakening gem that might be helpful for you. I used mine on my 4* Hyperion.
On your roster, Nick Fury and Corvus Glaive are both an instant 5/50 choice. Scrap the 3* and focus on 4* and if lucky, a 5*.