Got lucky....

Wayntos

Pulled a 5* Profess X and I have an mutant awakening gem!! Should I use it on him or save for another lucky day and Apocalypse!! I also have 5* Colossus , Iceman, Emma and Domino... should I use it on one of them?

Yodabolt21

Colossus

The_Sentry06

Apocalypse needs the gem less than Prof X.
None of those champs need an immediate awakening except maybe colossus.
If I were you, I would save it for OR or Namor

Wayntos

Cool forgot about OR thanks for the input I'll save for OR!! @Yodabolt21 and @The_Sentry06

Thicco_Mode

I don't know about prof x but colossus gains a lot from the gem