If you are playing with DM often, use it on him. If you can play tigra good enough, awaken her. If not wait for better worthy champs. Imo most of the mystic champs don't need awakening, I used mine on Doom, no regrets as his dupe is good to have against many fights and provides great prestige.
Personally I’d wait for mojo or doctor voodoo. No one, including the people you’ve listened to wait for, need to be awakened. Tigra out of the 5 you listed benefits the most.
It depends what you really need. If you're going for prestige, then wait for doom. Otherwise, I believe that Tigra gets a decent boost by having both her senses active with her ability awakened.
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