Depending on your current status those are my recommendations:
Omega Red if you have it very high sig. Ebony Maw for defensive purposes (AW, BG), same on Korg, King Groot Torch, Mole Man, Black Widow Deadly Origin, AA, Guillotine 2099,Apoc, Galan, Kingping, Diablo and Red Magneto are good for almost everything you could posibly play mostly (EQ, AW, BG, etc) I think Corvus lacks a lot of damage in Endgame content so I wouldnt recommend him. Anti-Venom is quite new to me but It has a lot of utility, but Idk if he is good for any endgame content. Same with Spider 2099 Red Hulk is not worth. Cable is a beast with Apoc synergy so If you play both together usually its a nice option. The remaining are just generally good options but not the best compared with the ones that I mentioned before that are good in every content (Omega Sentinel, Toad, Ultron, Hulkbuster, Guardian, Black Widow Claire Voyant)
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Omega Red if you have it very high sig.
Ebony Maw for defensive purposes (AW, BG), same on Korg, King Groot
Torch, Mole Man, Black Widow Deadly Origin, AA, Guillotine 2099,Apoc, Galan, Kingping, Diablo and Red Magneto are good for almost everything you could posibly play mostly (EQ, AW, BG, etc)
I think Corvus lacks a lot of damage in Endgame content so I wouldnt recommend him.
Anti-Venom is quite new to me but It has a lot of utility, but Idk if he is good for any endgame content. Same with Spider 2099
Red Hulk is not worth.
Cable is a beast with Apoc synergy so If you play both together usually its a nice option.
The remaining are just generally good options but not the best compared with the ones that I mentioned before that are good in every content (Omega Sentinel, Toad, Ultron, Hulkbuster, Guardian, Black Widow Claire Voyant)
I think the ones that are nice for almost everything you could posibbly play are Galan, Torch and AA.
But almost everything that you could R4 is worth it