Well, I could push any of them with generic and class sig stones to around sig 100. Does it changes anything?
I think Omega Red needs max sigs to have full damage output. At least the vids I've seen of highly skilled players using him with suicides on, he was max sig.
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Plus he's herc and completely broken.
Omega is another great choice due to healing and if you run suicides 24/7, he's a fantastic second choice after you awaken herc.