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'Thanos' nodes in labs: Which do you find most challenging?

So we've had a few weeks of Mystic labs which constantly generate Thanos-like 'Aspect of' effects. Largely just because I'm curious, which 'Aspect' node do you find most challenging, and why?
'Thanos' nodes in labs: Which do you find most challenging? 12 votes
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My top tip: Don't ever take Magik against AoC if you can avoid it. Especially if she's Awakened. I accidentally healed my opponent because I triggered Limbo just before the switch. This meant I recovered the 'damage' caused by the node giving Magik his health bar, then he got all his health back when the health bars switched back!