For keeping the champion alive the longest, Ghost rider is the best. He has a regeneration mechanic Which allows him to recover health in bursts. His Regen is awesome. Wasps damage is from her heavy attacks which are guaranteed crits. Loki is only useful for final boss of act 5 chapter 5 which I don't think your at yet. If you need a champ which can do many fights, pick Ghost Rider. If you need damage pick wasp
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For raw damage, Wasp.
For 5.4.6 Ultron, Loki. (About his only use really)
I don't understand what they mean.
Wasps damage is from her heavy attacks which are guaranteed crits.
Loki is only useful for final boss of act 5 chapter 5 which I don't think your at yet.
If you need a champ which can do many fights, pick Ghost Rider.
If you need damage pick wasp