Which science champ should I upgrade (all unduped)

Hawkcrew2000

They are all unduped

Lvernon15

Red Hulk

You can’t really go wrong between red hulk Gwen and cage, I wouldn’t go Modok unless you want a defender though, he’s not bad but he’s inferior to the others

TheRenegade98

Rulk benefits from poison and incinerate, lc is bleed immune and both have nice damage potential, I think that's your real debate here, lc is better duped

MegaGalactic

Luke Cage

LC’s duped ability is a huge plus but he still hits so hard, stuns, and then the bleed immunity.

JohnHS

Spider Gwen

It's between Cage and Gwen. They both have some pretty unique utility and some very nice damage. Luke can reduce passive power gain, is super tanky, and has stuns and ability accuracy reduction. Gwen has a high evade chance (but not when blocking, thank goodness), a strong evade/unstoppable counter, a super-petrify-stun thing on the SP2, a 220% chance to evade unblockable specials when not blocking (helps with stuff like the Collector, or unblockable machine guns, etc.) and enervate on the SP1. The fact that Gwen needs the dupe less pushes her over the edge for me.

Etjama

More information. Where are you in story? Do you have Domino? If so, Red Hulk would be your best option. Do you have Venom? Spider-Gwen benefits a lot from her synergy with him. Can you post a picture of your roster so we can see your needs? For instance, if you already have a high damage champ that stuns, you probably wouldn't want to go with Luke Cage.

Hawkcrew2000

Etjama said:

More information. Where are you in story? Do you have Domino? If so, Red Hulk would be your best option. Do you have Venom? Spider-Gwen benefits a lot from her synergy with him. Can you post a picture of your roster so we can see your needs? For instance, if you already have a high damage champ that stuns, you probably wouldn't want to go with Luke Cage.

I’m on Act 4.2.2 currently.