Domino has damage, omega has a bit less damage and 10x the utility, personally I put colossus second, held back by his reliance on either parry heavy or synergies
Omega with suicides and max sig destroys. There's so much hidden utility in those tentacle hits and no one would really expect there to be. The fact that he doesn't really need to hit the opponent to get good damage on them will bypass a lot and no one is immune to his DoT.
I think all the top mutants have the right to spot 1 but I feel Asif omega red edges out just above the rest due to his immunities/utility & that no one currently is immune to his DOT
Domino's crits and bleed are insane - 1.4k bleed for 5-6 seconds on a 5* unduped 3/45 without synergies. But the other champs are also really useful in other situations.
As much as I wanted to say Archangel, he's only really effective against non immune Champions. He gets neutered somewhat against poison immune and entirely neutered against Bleed immunes
Comments
Domino needs 2 synergy partners, Omega needs 1 and suicides. Collosus is good without anything, but shines with 2 synergy partners.
There other two just need themselves.
1. Domino
2. Namor
3. Sunspot
But the other champs are also really useful in other situations.