Almost all of the champions you put on your poll are great without the signature ability. I personally would use a gem on Colossus because his sig ability gives him a really good boost compared to the other champions you included. MY 2nd choice would probably be Human Torch because getting the pre-fight back in long quests is really useful.
I think colossusneeds the awakening most and sig 60 is enough for colossus don't take him to high.He is even good at sig 60 all you need is omega red synergy
Comments
quake is good for most but she can't do anything against archangel