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Need help building a good team/sinergy

As in thread, i'm pretty new to the game, and just played doing perfect parries 'till now. I'm currently doing act 4 100%, and wishing to get uncollectible asap. So i decided to make this post, which strategies should/can i use with my roster? Thanks to anyone who helps me!
https://imgur.com/a/c7n0ROR
https://imgur.com/a/c7n0ROR
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Also work on learning interactions between specific champs and champ abilities. That would go much further for you than synergies at this point.