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His sig ability allows him to nullify most buffs that serve as a disadvantage to him and pure of heart ability allows him to finish off most opponents who are weak to bleed and/or incinerate. Additionally, bad karma allows him to gain extra power to launch the nasty special attacks when pure of heart is active.
This is just personal opinion.
Nebs and Sentinel are also incredibly versatile
I'd also add BWCW! She's great: you can have the immunity you need, nullify, regen, lot of damage, power control... and she also boosts the attack of the team against villain. She helps me through a lot of contents!