I only have a 4* so can't speak for higher end but his dupe makes a pretty big difference as far as I can tell. If you want the out of this world damage, ability to go unblockable, debuff immune etc that all comes from his sig and breaking out "the real Nick Fury". Unduped he still has a nice bleed on light combo enders and decent damage but he doesn't stand out like he does with his sig.
Edit: to answer the question I wouldn't R2 him unduped. Being a 6* you really never know when you'll be able to awaken him and with that in mind those resources are too rare without the sig. Unless you're a top ally who can R5 champs pretty often
Yes. I just dupped my 5* and have been using him without the duppe just fine. With the Heimdall and Angela synergy you can give him a permanent fury in the beginning and tach charges won't fall off. So you can get all the perks of the tactical charges without life model decoy activated.
Hey @Feeney234 bro did you put your 6* nick fury to r2 bro cause i too need some stats help - reg him
No i did not. He is still at r1 unawoken. I do have a 5* at r5 sig 1 and he is an absolute savage. No regrets there. The awakening makes a HUGE difference.
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Edit: to answer the question I wouldn't R2 him unduped. Being a 6* you really never know when you'll be able to awaken him and with that in mind those resources are too rare without the sig. Unless you're a top ally who can R5 champs pretty often