I’d go with spot, without a counter he can be an annoying defender, and on attack he absolutely melts champs. Only down side is you take some chip damage from blocking, but from my experience the speed makes up for that
I'd keep idoom at r3 unless you're looking for prestige. I just brought Spot up to r4 and I love him. Awkward defender and beast on offense. Otherwise, Apoc, Diablo, and Scorpion are obvious choices
You've got a lot of great choices. I'm going to assume that you're looking for dual use rank up. Idoom melts all mutants and I didn't see a nimrod in your roster. QS if you can get his fight mechanic down is another good one. AA can end fights quickly if they opponent bleed and you can poison. Scorpion is another one. Great bursts damage and not a bad defender. But I think NF is the ultimate that you haven't ranked up yet. He can neutralize most defenders nodes. Has a second life which helps. And if they can bleed watch out.
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Guarantees a ban on BGs and very fast lvl3 health potion farming from spamming ROL WS 😉