Considering difficulty vs level Annihilus is definitely the most difficult. Doom is the final boss and is difficult, while annihilus is the second one and is still quite difficult to face IMO. Not that bad but considering that he’s the second boss I’d say that annihilus is quite difficult.
What’s the counter or strategy for Sym Supreme? That 10 second timer is brutal. I am trying quake, but if I mess up once I’m dead.
All the damage is stored in that buff and if you make sure he doesn't hit you (even blocking) that damage will hit him when the timer runs out. If he makes contact, the stored damage hits you
Annihilus hands down, the unstoppables and obliterating strikes were the bane of my battles. Dr doom is easy once you get used to evading sp1 and sp2, and to be careful around his aura.
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MrF was hard. Don't really know why