If you have enough skill and enough revives/potions then you can probably do it with a team of Ghost Rider, Hyperion and Iceman. Daredevil is a good option too.
damn. so. definitely hyperion(he'll need the rank up), vision, ghost rider, x-23. Hyperion will get you through the buffet and masochism levels, you'll just have to change how you use him in each level. You will need to rank up vision though by the time you get to the collector. but yeah, it can be done.
take iceman if you want, but doesn't provide much support for the collector.
If it was me, I would probably rank the Ghost Rider and Hyperion to at least R3, and actually GR is a good candidate for first R4, and take Iceman, Vision, and X-23 to R5 first. I'm not saying all that firepower is necessary for 5.2, but if I had it I would use it to minimize my costs.
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Make her 5/50 then it will be a piece of cake with her.
take iceman if you want, but doesn't provide much support for the collector.