Realm of Legends

So I've been thinking about making the realm of legends and I'd like to know which champions are recommended for this challenge. I am currently in Act 5, Chapter 1. Act 4 100% explored. Would you like to help me, please?
PS: These are my best


PS: These are my best


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Bring a strong poison immune for scarlet witch.
If you can't hold a combo bring 3* guillotine or void for wolvie.